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Gradual reduction gives your body time to adjust

Mily A, Rekha RS, Kamal SM, Arifuzzaman AS, Rahim Z, Khan L, Haq MA, Zaman K, Bergman P, Brighenti S, et al

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Recent clinical trials on glutamine metabolism inhibition mainly focuses on using CB-839 to target glutaminase (NCT02071862, NCT02071888 and NCT02071927 for solid tumors, lymphoid, and myeloid malignancies respectively) [24, 62]