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In this context, research strategies aimed at the selective inhibition of FOXO proteins including the use of peptide analogs such as FOXO4-DRI represent a promising approach for investigating the modulation of metabolic pathways, with potential relevance to diabetes-related complications

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A 2021 review covering 30 years of clinical data described cerebrolysin as demonstrating "a disease-modifying effect by slowing down the progression" of Alzheimer disease, but this language outpaces what the clinical trial designs can definitively prove