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230232 Historically, the first applications of metalloregulators as biosensors were based on engineering living bacteria, where a regulated promoter was positioned upstream of a reporter gene, with strategic modifications of the bacterial chassis allowing for the desired intracellular bioaccumulation and sensitivity

[DOI] [PubMed] [Google Scholar] 46.Engelhardt B., Sorokin L

Central obesity is associated with increased secretion of adipokines, which promote the release of pro-inflammatory mediators from peripheral tissues, elevating circulated androgen levels

As the liver becomes compromised, it struggles to meet its own glutathione needs and there may be little surplus glutathione secreted into the blood for other organs of the body

Ventromedial hypothalamic melanocortin receptor activation: regulation of activity energy expenditure and skeletal muscle thermogenesis