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10.1016/j.talanta.2018.12.049 83

Only in nature we found the right balance of energy, nutrients and wellbeing

Jornal Brasileiro De Reproducao Assistida

It has been shown that rhein inhibits CYP2C9, CYP1A2, CYP2E1, CYP2D6 and CYP3A enzymes in rat liver (Tang et al., 2009)

More recently, experimental evidence points oxidative stress and mitochondrial dysfunction as one of the common pathophysiological mechanisms responsible of neurotoxicity in CIPN