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Sherry A McKee, Tracy Falba, Stephanie S O'Malley, Jody Sindelar, Patrick G O'Connor, Smoking status as a clinical indicator for alcohol misuse in US adults, 2007.

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Therefore, [synthetic nicotines] track and traceability is another huge factor that would bring a responsible manufacturer into closely considering the substitution of synthetic nicotine for natural nicotine. However, McQuillan did not uniformly concur with Cassels-Smiths observations regarding tobacco-derived nicotine