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The matrix proteins clusterin and tenascin, and connective tissue growth factor (CTGF) have been proposed to be the bioactive factors in NCCM [60, 67, 68]

The pathophysiology of IC/BPS is poorly understood, and theories include chronic inflammation, autoimmune dysregulation, bacterial cystitis, urothelial dysfunction, deficiency of the glycosaminoglycan (GAG) barrier and urine cytotoxicity

This peptide may help support metabolic balance, body composition goals, and overall wellness

A number of researchers have called for the replacement of cyanocobalamin in supplements with other, safer forms of vitamin B12 listed above