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Assuming 40 mL per puff and 15 puffs per e-cigarette unit (according to several manufacturers) [4], each e-cigarette unit would generate approximately 1.89 g of acrolein, which is less than the levels of acrolein emitted by a conventional tobacco cigarette (18.398.2 g) [51]

E-cigarette sales in the United States surged nearly 47% from 2020 to 2022 to more than 22 million units per month, despite an FDA crackdown on the products, although nearly 70% of youth e-cigarette users have reported trying to quit in the past year

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