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After youre comfortably seated, a small catheter is placed into a vein and the customized solution is slowly infused

Sermorelin is a GHRH-receptor analog, while Ipamorelin is studied as a selective growth hormone secretagogue (ghrelin) receptor agonist a distinct mechanism of action

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Clinical relevance has yet to be determined

There are currently 3 PK activators in clinical development for SCD: mitapivat (AG-348), etavopivat (FT-4202), and the second-generation molecule AG-946