Recent reviews indicate that suitably engineered CQDs can traverse the BBB via receptor-mediated endocytosis and adsorptive-mediated transcytosis, with surface charge and amphiphilicity influencing endothelial interactions and uptake efficiency, although the relative contributions of these pathways are not yet well defined [143]
Kutch JJ, Ichesco E, Hampson JP et al: Brain signature and functional impact of centralized pain: A multidisciplinary approach to the study of chronic pelvic pain (mapp) network study
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