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Recommendations for converting a patient who is not doing well while taking LT4 from LT4 monotherapy to combination therapy have been published (218)

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[PubMed: 18094741] (45 year old man developed fatigue and body aches and took 4 g of acetaminophen for 2 days developing jaundice, stupor and coma [bilirubin 11.3 mg/dL, ALT 580 U/L, Alk P 406 U/L, IgM anti-HEV positive]

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J Nutr Biochem 22:118694

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Injections bypass this entire process, delivering B12 directly to your bloodstream

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doi: 10.4049/jimmunol.1502046 177 ZengHYangKCloerCNealeGVogelPChiH

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