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It induces inflammation, insulin resistance, and stress, disrupting glucose metabolism

Similarly, in bronchial epithelial cells cigarette smoke extract (CSE) increases LC3B-II expression and induces autophagy while knock-down of autophagy proteins LC3B and Beclin-1 protect against CSE-induced apoptosis 11

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It tastes great, lasts over an hour, feels very comfortable and non-irritating in the mouth, and is worthy of a place of honor in my refrigerator

L., Hukkanen, J., & Jacob, P., 3rd (2009)