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Thyroid hormone receptor-beta agonist HSK31679 alleviates MASLD by modulating gut microbial sphingolipids

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Furthermore, dihexa possess neuroprotective properties, as other animal studies have demonstrated anti-inflammatory and anti-apoptotic effects of the drug

Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment

Because composite antioxidant assays reflect extracellular antioxidant pools and are influenced by multiple circulating factors beyond glutathione, future studies should incorporate functional endpoints alongside PK and expanded sulfur-metabolism panels to clarify physiological relevance and optimal dosing

Second, EGCG could upregulate Keap1-Nrf2-ARE pathway, to further induce the expression of SOD, GPX, GSH and catalase