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These APX forms undergo structural and functional transitions between HMW and LMW forms

4.4 Sulfur-containing amino acid metabolism and renal protection 4.4.1 Metabolic fate of methionine and cysteine Sulfur-containing amino acids (methionine and cysteine) play critical roles in maintaining redox balance and producing protective gaseous signaling molecules (140)

Placental transfer of nicotine and carbon monoxide in tobacco smoke can induce placental hypoxia, leading to utero-placental insufficiency and inadequate delivery of O 2 and nutrients to the developing fetus [282]

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