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DSIP contributes to hypertrophy and hyperplasia in skeletal muscle by inhibiting somatostatin, a protein that is produced in muscle cells and acts on muscle growth

The latter has been widely described by Kerley et al

Gast A, Bermejo JL, Claus R, Brandt A, Weires M, Weber A et al

Eguren C, Navarro-Blasco A, Corral-Forteza M, Reolid-Prez A, Set-Torrent N, Garca-Navarro A, et al

Elevated IGF-1 levels are observed in patients experiencing their first episode of schizophrenia (119, 120) (Figure 2)

IGF-1 and its modified synthetic versions such as Long R3 IGF-1, des(1-3)IGF-1, and R3-IGF-I, have mitogenic effects, which speed up cell replication in laboratory models of different tissues