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In Japanese patients with hyperuricemia who were studied in detail, heritable ABCG2 dysfunction was observed in up to half of the study population investigated, and its population-attributable contribution to hyperuricemia was as high as 30%, much higher than the contribution of non-genetic factors such as overweight/obesity, heavy alcohol consumption and aging

April 2025 We continue to await a decision on plaintiffs' appeal of Judge Cote's decision to grant summary judgment to the defendants

Luteolin prevents THP-1 macrophage pyroptosis by suppressing ROS production via Nrf2 activation

doi: 10.1159/000458816

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Reading the gaps in reverse points to what a stronger evidence base would require