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& Kierszenbaum, A

For example, the main clinical manifestation of OSF is a burning sensation and intolerance to spices, and as the disease progresses, patients experience reduction in mouth opening, which not only causes pain, poor oral hygiene and impaired chewing and swallowing, but also affects patients speaking and appearance, causing psychological issues and limitations in social activities (Wang et al., 2022)

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BMC Biotechnol 15:84 Savoca MP, Tonoli E, Atobatele AG, Verderio EAM (2018) Biocatalysis by transglutaminases: a review of biotechnological applications