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Neuropsychopharmacology (2017) 42(8):161929.10.1038/npp.2017.21 52 KorytinaGFAkhmadishinaLZViktorovaEVKochetovaOVViktorovaTV

They are mostly used in the movies as substitutes for marijuana, pipe tobacco, or roll your own cigarette fillers

Using a cleaning product with degreasing properties, such as the interior detailers from Turtle Wax or Meguiar's, can be helpful in removing the film that smoke leaves behind

Nicotine acts as a stimulant in low doses but can be a nervous system depressant in high doses -- in extremely high doses it can depress the respiratory system enough to be lethal

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