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Its biosynthesis is a two-step enzymatic cascade, including first a specific -ligation of glutamate and cysteine by -glutamate-cysteine ligase (GCL) and then the formation of peptide bond between this dipeptide and glycine by glutathione synthetase (GS)

doi:10.4103/ijd.IJD_582_17 20Kardaun SH, Sekula P, Valeyrie-Allanore L,

The reduced form GSH is the active form of the molecule, it is the most abundant and it is found inside the cells in millimolar concentrations in the range of 110 mM (highest concentration in liver) (Figure 1) which provides its reductive power

Allergic rhinitis is an allergic reaction that causes symptoms such as watery eyes, sneezing, itching, runny nose and nasal congestion ( Common triggers of allergic rhinitis include animal dander, pollen and molds

Additionally, individuals considering glutathione troches should discuss the potential risks and benefits with their healthcare provider before starting treatment, especially if they have any underlying medical conditions or are taking other medications