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Description

Prevalence rates in multiple sclerosis increase with the patients latitude, and scientific studies have proven that colder climates are harsher for our immune and central nervous systems

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This HO-CO pathway has been recently proposed to be involved in the defence against oxidative stress and the deleterious effects of NO, since it removes the cytotoxic free heme, and produces some molecules with antioxidant and anti-inflammatory effects, such as biliverdin and CO [8, 3840]

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doi: 10.1039/c8fo02461h 79

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For both drugs, extracellular GT activity is an essential and limiting step in their activation into membrane permeable compounds (Garnier et al., 2014)

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Aw TY, Ookhtens M, Ren C, Kaplowitz N: Kinetics of glutathione efflux from isolated rat hepatocytes

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