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It is the first triple-hormone-receptor agonist to reach advanced clinical trials, activating three distinct metabolic pathways that individually would each justify their own drug development program

This is not a regulatory recap

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The chemical reaction involves the deprotonation of C4 in the A ring of the steroid substrate, thereby enabling the double bond between C5 and C6 to isomerize to a double bond between C4 and C5 (Figure 2)

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