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Its also one of the most aggressively marketed skin-lightening shortcuts in the country, often by clinics that have no business handing out IV drips

Methylation Capacity Second, NNMT inhibition affects cellular methylation capacity: SAM is required for hundreds of methyltransferase reactions throughout the cell, and NNMT's consumption of SAM can deplete this critical resource, while the SAH produced by NNMT is a potent product inhibitor of many methyltransferases

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Consistency is much more effective than mega-dosing