With regard to discrepancies in mRNA and protein levels of mitophagy constituents, the fact that mitophagy proteins are actively broken down together with the mitochondrion during mitophagy and need to be replenished (by transcriptional) upregulation of the respective genes, may contribute to apparently discrepant findings
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6A, Nrf2-shRNA transfection significantly reduced Nrf2 expression (approximately 70%) in HBECs compared with negative control (NC) group
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