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J Cell Biol 103: 755766, 1986
Its a tripeptide (made of three amino acids: cysteine, glutamic acid, and glycine) that your body naturally produces
Even though at present the strongest arguments in favor of using this compound pertain only to topical applications, further investigations of this substance remain relevant
Olsson LM, Lindqvist AK, Kllberg H, et al
The main pathophysiological mechanism of HE are based upon evidence of the accumulation of toxic substances, including the ammonia, glutamine, manganese, false neurotransmitters, inflammation, short chain fatty acids, oxidative stress, mercaptanes, neurosteroids, or low grade edema.2 However, the most widely accepted is that accumulation of endogenous and gut-derived ammonia crossing the blood-brain barrier, and functional changes in various neurotransmitter systems.3 Thus, current therapies focus on pathogenesis previously accepted, and the roles of drugs were critically estimated through systematic review according to methodology of Evidence-based Medicine (EBM), such as non-absorbable disaccharides,4 rifaximin,5 L-ornithine-L-aspartate (LOLA),6 naloxone7 have been widespread used now
