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Funding: This work was supported by a grant from the Caribbean Public Health Agency as well as funding by the Children's Nutrition Research Center, Baylor College of Medicine

The global obesity epidemic and its associated metabolic disorders urgently require more effective therapeutic interventions, particularly multi-pathway targeting therapies

These effects were associated with increased F-actin formation and activation of focal adhesion kinase (FAK) and paxillin phosphorylation, signaling events central to cell attachment and cytoskeletal remodeling during tissue repair processes [4]

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The following Tables 1, 2 illustrate different vaccination trials for blood and sexual stage subunit and crude antigenic extracts so far described in the literature