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Endogenous compounds, including signaling molecules derived from arachidonic acid and associated enzymes, have the ability to bind and stimulate endogenous cannabinoid receptors, leading to elevated quantities of RNA and protein [104]

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Once ipamorelin binds to GHSR-1a, it activates G-protein-coupled receptor signaling that triggers calcium influx and cyclic signaling pathways associated with GH vesicle exocytosis

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