& Patrone, P
Further research has revealed that, with the assistance of the coactivator PGC-1, FOXO1 regulates glycogenolysis and gluconeogenesis by modulating the expression of G6PC and PCK1
10.3389/fnins.2018.00019 [DOI] [PMC free article] [PubMed] [Google Scholar] 28.Frye RE, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, et al
NNMT (nicotinamide N-methyltransferase) is an enzyme found in fat cells and other tissues that can become overactive in certain metabolic conditions
LRP1 knock down mice model The adeno-associated virus 8 that knock down the LRP1(sh-LRP1, 5-GGATTCCACTAGATCCCAATG-3) gene in mouse livers was constructed by Vigene Bioscience (Shandong, China)
Flow cytometry Exponential phase cells (OD 600 ~ 1.52.0) in YNB were diluted to OD 600 0.5, then 1 mL samples washed twice in PBS before resuspension in 1 mL PBS