Tang D, Chen X, Kang R, Kroemer G (2021) Ferroptosis: molecular mechanisms and health implications
Our study indicates that ferroptosis of CRC DTP cells presents a novel strategy to prevent chemotherapy or targeted therapy regimen resistance and tumor recurrence
doi: 10.3389/fphys.2021.625287 186 OzonoffAJayaveluNDLiuSMelamedEMillirenCEQiJet al
Methods: A bidirectional Mendelian randomization (MR) study was performed to investigate the causal effects by using 3 main methods (Variance Weighted (IVW), Weighted Median (WM), and MR-Egger regression) in the European population
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Result:The average number of eye-spots (meanSEM) is 5.360.29 (n=46), 7.790.45 (n=34) and 8.780.61 (n=32) in untreated controls, 2 mM L-Buthionine-(S,R)-sulfoximine (BSO) and 20 mM BSO treated mice, respectively