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Altered cytokine profile is detectable already in cord blood of neonates of smoking mothers, with decreased IFN- and increased IgE and IL-13 levels underpinning the capacity of prenatal cigarette smoke exposure to increase the risk of infections and to potentially induce a proclivity for allergy in early life [72,73]

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Children exposed to SHS after birth had a higher risk of bronchial asthma at 3 years old than unexposed children (aOR 1.12, 95% CI 1.041.21)