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Description

However, we previously reported intracellular levels of these mediators in relation to GPX4 activity (7) that are likely similarly altered here

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Ca 2+ is not metabolized and an overload of mitochondrial Ca 2+ may break down the electrochemical proton gradient resulting in a deficit of ATP followed by necrosis [89]

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doi: 10.1152/physiologyonline.2001.16.3.118

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