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Both studies showed that therapy with AuNPs reversed the behavioural symptoms caused by PD, indicating the effective protective impact of AuNPs on dopaminergic neurons without any toxic effects

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the identified protein biomarkers were confirmed by performing molecular analyses

As it was previously demonstrated that lysine lactylation was induced by neural excitation, a key molecular mechanism for the development of epilepsy [96], with the detailed results showing the positive association of increase of lysine lactylation and the expression of the immediate-early gene marker of neuronal activity c-Fos [97], it is hypothesized that histone delactylation by HDAC1-3 may inhibit the development of epilepsy and prevent seizures

The overall cost of treatment depends on the number of sessions required, which typically ranges from 10 to 30 injections for visible skin whitening