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A 2005 costbenefit analysis of injured ED and hospitalized patients advised routine implementation of screening and brief intervention of all trauma patients after finding that 27% of all injured adult patients in the study were candidates for a brief intervention for alcohol, and factoring in health care systems level costs estimated $3.81 saved for every $1 spent on screening and intervention [44]

British Medical Journal: Tobacco Control

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In contrast, no significant differences were observed in the total content of acids among the four samples

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Recent studies indicate that accumulation of cadmium in the blood mediates progression of CKD and places smokers at higher risk for all-cause mortality