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It depends on the peptide, dosage, and individual factors

Treatment with once-weekly cagrilintide (0.16, 0.30, 0.60, 1.2, 2.4, and 4.5 mg) in combination with semaglutide 2.4 mg for 20 weeks was not associated with an increase in adverse events compared with placebo in combination with semaglutide 2.4 mg, with no unexpected safety or tolerability findings

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The intestinal microflora regulates immune, metabolic, and endocrine functions [53, 79, 80]

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