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Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps

Anti-inflammatory effects: Multiple pathways

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However, during clinical translation, the structural complexity of the human liver, the heterogeneity of disease microenvironments, and interspecies differences often lead to suboptimal performance of nanodrugs in human trials despite promising results in preclinical animal studies

doi: 10.1038/s41581-023-00689-x 17 LongZLuoYYuMWangXZengLYangK

In addition, liver-derived acylcarnitine can also be taken up by intestinal epithelial cells and used for mitochondrial oxidative metabolism, providing additional energy for intestinal cells [218]