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Furthermore, the log10-transformed serum cotinine level exhibited a non-linear inverted U-shaped association with constipation in individuals with poor dietary quality ( P overall = 0.0207, P non-linear = 0.0427)

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Tobacco causes teeth to yellow and creates excess dental plaque

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Recently, it has been shown that even at a 10:1 ratio, nicotine does not have a significant effect on A and its aggregation pathway and may affect A amyloid burden by affecting A production, degradation, or/and localization [205]