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Nicotine could contribute to this progression by aggravating vasoconstriction, although other tobacco smoke toxins are also likely to be contributing to progressive vascular injury. In laymans terms this tells us that nicotines impact as a vasoconstrictor (shrinking blood vessels which increases blood pressure) can contribute, alongside the other chemicals in cigarette smoke, to more severe conditions brought about by prolonged hypertension

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The guys lives his roles

I think they kind of go together anyway

Nicotine poisoning in children can cause nausea, vomiting, convulsions, weakness, trouble breathing, unresponsiveness, and death

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