When higher levels of acetaminophen are ingested, the livers supply of glutathione is depleted and NAPQI causes liver damage.[ref] Related article: Genetic variants that increase the risk of liver damage from acetaminophen Studies on the impacts of low glutathione levels: Glutathione levels in the body are fairly tightly regulated, and balance is key
While glutathione is a naturally occurring substance, injecting it bypasses the bodys natural filtration systems and introduces high concentrations directly into the bloodstream or muscle tissue
Treatment with Noopept was found to significantly reduce levels of conjugated dienes, ketotrienes, malondialdehyde, and increase activity of superoxide dismutase
This process involved metabolic dysfunction that results in increased production of cytosolic and lipid ROS, independently of mitochondria
Lantibiotic bacteriocins produced by the widespread cariogenic bacterium S.m in the oral cavity have also been shown to perturb the intestinal microbiota, suggesting a direct mechanism by which these oral bacteria contribute to gut dysbiosis (Yonezawa et al., 2021)
Key Actives: Glutathione, Niacinamide, Hyaluronic Acid, Vitamin C, Botanical Extracts