IL-2, interleukein-2
SURMOUNT-1 (Jastreboff et al., NEJM 2022) reported 22.5% body weight loss at 72 weeks at the 15 mg dose
It works by reducing oxidative stress and influencing melanin production, which can affect skin tone and clarity
In particular, K-F rings due to secondary copper overload may be seen in primary biliary cirrhosis, intrahepatic cholestasis, or chronic hepatitis.23,24 Another ophthalmologic finding of Wilsons is deposits of copper in the anterior and posterior lens capsule called a sunflower cataract.25 These, too, do not interfere with vision and can resolve with chelation therapy
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doi: 10.1042/bst20130220 84 WoloskerH.ShethK