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doi:10.1016/j.metabol.2012.01.017 [54] Shoaib M, Shehzad A, Omar M, et al

Additionally, SREBP-1a has been associated with hepatic inflammatory responses

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The potential to counteract these effects has been demonstrated with IL-1 receptor antagonists, which have been shown to improve glucose tolerance and enhance insulin production [571]

Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferatoractivated receptor