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In preclinical studies, carotene tended to maintain myocardial GSH levels and GPX activities and reduce oxidative stress in vitro and in vivo [143, 144]
Biomed Pharmacother 165:115215
Accumulation of GSSG over time spent awake should decelerate glutathione peroxidase activity through product-dependent inhibition and thereby increase NADP+ concentration in the brain (as indeed occurs in sleep deprivation
In freeze-dried form the material stays stable for extended bench storage
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