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glutathione ai

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Description

Through direct binding to presenilin enhancer 2 (PEN2) on the lysosomal membrane, metformin inhibits v-ATPase via interaction with ATP6AP1, triggering recruitment of the AXIN-LKB1 complex to the lysosome (Ma et al., 2022

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Most peptides require subcutaneous (SubQ) injections

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The second step is catalyzed by GSH synthase, which adds glycine to -glutamylcysteine to form -glutamylcysteinylglycine or GSH

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In parallel with this investigation, we synthesized -EC from GSH by NsPCS in 500 mL scale reaction and purified by anion-exchange resin column

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