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Gamma-glutamyl transpeptidase deficiency leads to glutathionuria, glutathionemia, growth failure, cataracts, lethargy, shortened life span, and infertility

These high correlations are consistent with the hypothesis of a mechanistic link between antioxidant and glutamatergic systems in the human brain such that under steady-state conditions, low levels of glutathione are associated with low levels of glutamatergic neurotransmission [17]

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doi: 10.1053/j.jrn.2014.10.002

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