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TIGAR plays neuroprotective roles in KA-induced excitotoxicity through reducing neuroinflammation and improving mitochondrial function

85,91,114,257 Subsequently, procaspase-1 transforms into its mature form, caspase-1

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Its primary mechanism involves upregulation of the hTERT gene, which encodes the catalytic subunit of telomerase -- the enzyme that adds TTAGGG repeats to chromosome ends

Both fasting-induced leptin reduction and GH increase are blunted in Cushing's syndrome and in simple obesity