BenchenaneKBerezowskiVAliCFernndez-MonrealMLpez-AtalayaJPBrillaultJet alTissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptorrelated protein-mediated transcytosis
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Upon H2O2 challenge in vitro, ABI1 and ABI2 are inactivated rapidly, with an IC50 value of 140 mM for ABI1 and 50 mM for ABI2 in the presence of physiological concentrations of GSH (Meinhard and Grill 2001
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Potential risks Serious risks and adverse events include: Allergic reaction to the medications or dye used in the injection Shoulder infection Depigmentation of the skin around the injection site (a whitening of the skin) Local fat atrophy around the injection site (thinning of the skin) Rupture of a tendon located in the path of the injection Nerve damage near the shoulder joint Bleeding at the injection site In addition to the above, corticosteroid injections increase the risk of: High blood pressure High blood sugar Decreased immune function Decrease in bone mineral density Bone infection (osteonecrosis) Reproductive hormone imbalance Metabolic changes (eg, increased appetite, weight gain, and fluid retention) These risks are typically associated with higher doses of corticosteroids, multiple injections, and for people with underlying medical conditions such as diabetes and heart problems
Cynader, Pyruvate Released by Astrocytes Protects Neurons from Copper-Catalyzed Cysteine Neurotoxicity
