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We retested these compounds in IMR90 ER:RAS cells, and in a melanoma cell line, SK-MEL-103, in which we induced senescence by treatment with the chemotherapeutic agent etoposide or the Aurora kinase inhibitor tozasertib (Supplementary Fig

Within the ER, hexose-6-phosphate dehydrogenase converts glucose-6-phosphate and NADP + to 6-phosphogluconate and NADPH

It has been studied in a range of musculoskeletal pain and injury conditions

Their images were taken following the Olympus DP2-SAL firmware program (Olympus Inc

Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance

Burrill, J