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10.1161/STROKEAHA.113.001183 [DOI] [PubMed] [Google Scholar] 38

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Furthermore, several micro-RNAs known to regulate the expression of genes involved in counteracting ROS/RNS are differentially regulated in ALS patients

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High doses of pyridoxine are associated with peripheral neuropathy, whereas high doses of the active form, pyridoxal-5-phosphate, are not (Hadtstein & Vrolijk, 2021)