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All SIRTs share a common conserved NAD + -binding domain but differ in their amino and carboxy-terminal regions, catalytic activity, and cellular functions [66,67]

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Fluoro488 Conjugated Goat Anti-Rabbit IgG (BA1127) was used as secondary antibody at 1:500 dilution and incubated for 30 minutes at 37C

GC18705 ML-210 DPI10 ML-210 is a prodrug that selectively inhibits GPX4 covalently with an EC 50 of 30nM

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Chlorogenic acid, a phenolic compound with various biological activities, ameliorates liver injury in an experimentally induced model of oxidative stress (Pang et al., 2015)