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Research Applications & Laboratory Models 9.1 In Vitro Models 9.2 Ex Vivo & In Vivo Models 9.3 Key Experimental Considerations Dose Range: Typical in vivo doses range from 0.110 g/kg for BPC-157, 0.520 mg/kg for TB-500 Route: Intraperitoneal (IP), subcutaneous (SC), topical, or oral depending on model Duration: Acute studies (37 days) vs

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Sterile handling Plan bacteriostatic water, alcohol swabs, sterile syringes, cold storage, and sharps disposal before reconstitution

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Holmboe L, Andersen AM, Mrkrid L, Slrdal L, Hall KS (2012) High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients

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