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Kumar S, Bandyopadhyay U

Elevated resistin levels activate the c-Jun N-terminal kinase (JNK) pathway, which phosphorylates IRS-1 at serine residues, impairing its function and resulting in reduced glucose uptake and heightened insulin resistance ( In a recent investigation involving insulin-resistant rats subjected to a high-fat diet (Wang X

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In the context of HF, idebenone has been shown to inhibit myocardial lipid peroxidation, thereby contributing to cardiac protection

Mitochondrial Function & Bioenergetics Intracellular glutathione pools, particularly within mitochondria, are critical for maintaining mitochondrial integrity and function