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The survey has a standardized questionnaire consisting of questions about main background characteristics, tobacco use, and data related to tobacco control measures such as being exposed to secondhand smoking, seeing tobacco ads, promotions, and sponsorship, utilizing smoking cessation, and others

We found that the antagonistic functions integrated in E3 ubiquitin ligases can prevent any undesirable sustained activation of downstream genes when E3 ubiquitin ligases are destabilized by unexpected perturbations