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Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study

One small study found that a dosage of 1,400 mg 3 times per week for 4 weeks was well tolerated (9)

16 Statistical significance was assessed by repeated measures ANOVA with post-hoc paired Students t -test

Int J Dermatol 2011;50(12):15701578

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